Grace Chao, B.S.
Pronouns: she, her, hers
Doctoral Student
SDSU / UC San Diego Joint Doctoral Program in Cell and Molecular Biology
San Diego
- gchao2968@sdsu.edu
- Location
- GMCS 326
5500 Campanile Dr
San Diego, CA, 92182 - Mail Code
- 4614
- Fax
- Links
- Website
- Accounts
Areas of Expertise
Cell and Molecular Biology
Student Opportunities
Bio
The conversion from isocitrate to α-ketoglutarate by IDH1 is the main source of NADPH in peroxisomes. Mutations in IDH1 prevent this conversion and can affect plasmalogen biosynthesis, β-oxidation of very long chain fatty acids, and α-oxidation of phytanic acid. I aim to use lipidomics and cellular assays to establish the intracellular consequences of IDH1 mutations that drive cancer.